Double marker (Delfia)

Double Marker (DELFIA)

Test Name: Double Marker Test (DELFIA)
Sample Type: Maternal blood / Serum
Method: DELFIA (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay)

About the Test

The Double Marker Test is a prenatal screening test generally performed during the first trimester of pregnancy. It measures two biochemical markers in maternal blood:

• Free β-hCG
• PAPP-A (Pregnancy-Associated Plasma Protein-A)

The results are combined with maternal age, gestational age and ultrasound findings such as NT (Nuchal Translucency) to estimate the risk of certain chromosomal conditions.

What Does It Screen For?

It helps assess the risk of:

• Down syndrome (Trisomy 21)
• Edwards syndrome (Trisomy 18)
• Other chromosomal abnormalities as part of combined first-trimester screening.

Who May Be Advised This Test?

• Pregnant women undergoing first-trimester prenatal screening
• Usually performed around 11–13+6 weeks of pregnancy, as advised by the treating obstetrician.

Important Note

This is a screening test, not a diagnostic test. A high-risk result does not confirm a chromosomal abnormality. Your doctor may recommend further evaluation or diagnostic testing if required.