Double marker (Immulite)

Double Marker (Immulite)

Test Name: Double Marker (Immulite)
Sample Type: Maternal serum
Method: Immunoassay (Immulite platform)

About the Test

The Double Marker test is a first-trimester prenatal screening test used to estimate the risk of certain chromosomal abnormalities in the developing baby. It measures two biochemical markers in the mother’s blood:

• Free β-hCG
• PAPP-A (Pregnancy-Associated Plasma Protein-A)

The results are combined with maternal age, gestational age, and ultrasound findings such as NT measurement to calculate an individualized risk estimate.

Why is it Done?

• Screening for risk of Trisomy 21 (Down syndrome)
• Screening for Trisomy 18 (Edwards syndrome)
• Helps guide further prenatal evaluation when indicated

When is it Recommended?

Usually performed during the first trimester, around 11–13+6 weeks of pregnancy, as part of combined first-trimester screening.

Important Note

This is a screening test, not a diagnostic test. A high-risk result does not confirm a chromosomal abnormality. Your doctor may recommend further evaluation or diagnostic testing based on the overall risk assessment.