Test Name: DNPH (Dinitrophenylhydrazine) Test, Urine
What is it? The DNPH test is a qualitative screening test for reducing substances, particularly carbonyl compounds such as ketones and certain keto-acids, in urine. It may be used as part of the evaluation of suspected inborn errors of metabolism, especially disorders affecting amino-acid and organic-acid metabolism.
Clinical Indications
Suspected inherited metabolic disorders
Unexplained metabolic acidosis
Recurrent vomiting or poor feeding
Developmental delay or neurological symptoms
Unusual urine findings or metabolic screening abnormalities
Evaluation of suspected amino-acid/keto-acid metabolism disorders
Sample: Urine Method: Qualitative chemical reaction Report: Positive / Negative or as per laboratory protocol
Clinical Note: A positive result is not diagnostic by itself. Further biochemical and molecular investigations may be recommended to identify the underlying metabolic disorder.
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