Rheumatoid Factor (RA) – Quantitative, Serum (R0004)
Test Overview
The Rheumatoid Factor (RA) Quantitative test measures the level of rheumatoid factor antibodies in the blood. These antibodies are commonly associated with autoimmune conditions, especially rheumatoid arthritis, where the immune system mistakenly attacks the joints.
Why This Test is Done
- To help diagnose rheumatoid arthritis (RA)
- To differentiate RA from other autoimmune or inflammatory disorders
- To monitor disease progression and treatment response
- To support diagnosis of conditions like:
- Sjögren’s syndrome
- Chronic infections
- Other connective tissue disorders
Sample Type
Preparation
- No fasting required
- Inform your doctor about any ongoing medications
Test Method
- Quantitative analysis (commonly by immunoturbidimetry or nephelometry)
Normal Range
- Typically: < 20 IU/mL
(Ranges may vary slightly depending on laboratory standards)
Interpretation of Results
-
Normal (Negative): Low or undetectable RF levels
-
Elevated RF Levels May Indicate:
- Rheumatoid arthritis
- Autoimmune diseases
- Chronic inflammatory conditions
⚠️ Note: A positive RF result alone is not sufficient for diagnosis. Clinical correlation and additional tests are required.
Symptoms That May Require This Test
- Persistent joint pain and swelling
- Morning stiffness lasting >30 minutes
- Fatigue and weakness
- Symmetrical joint involvement
Reporting Time
Benefits of the Test
- Early detection of autoimmune disorders
- Helps guide treatment decisions
- Useful for monitoring disease activity
Who Should Take This Test
- Individuals with joint-related symptoms
- Patients suspected of autoimmune disorders
- Those with a family history of rheumatoid arthritis
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