FSH (Follicle Stimulating Hormone), Serum – F0006

Test Overview

The FSH (Follicle Stimulating Hormone) test measures the level of follicle-stimulating hormone in the blood. FSH is a key hormone produced by the pituitary gland and plays a vital role in regulating the reproductive system in both males and females.

Purpose of the Test

This test is used to:

• Evaluate female fertility and ovarian function
• Assess menstrual irregularities
• Diagnose menopause or perimenopause
• Investigate male infertility (sperm production issues)
• Detect disorders of the pituitary gland or hypothalamus
• Evaluate precocious or delayed puberty in children

Clinical Significance

In Females

• Regulates growth of ovarian follicles
• Helps control the menstrual cycle
• Elevated levels may indicate:
  • Ovarian failure
  • Menopause
  • Polycystic ovarian syndrome (PCOS)
• Low levels may suggest pituitary or hypothalamic dysfunction

In Males

• Essential for sperm production
• High levels may indicate testicular failure
• Low levels may suggest pituitary disorders

When is the Test Recommended?

• Irregular or absent menstrual periods
• Difficulty in conceiving
• Symptoms of menopause (hot flashes, irregular cycles)
• Low sperm count or infertility in men
• Early or delayed puberty in children

Sample Type

• Serum

Preparation

• No fasting required
• In women, timing of the test may depend on the menstrual cycle (as advised by physician)

Normal Reference Range (may vary by lab)

Females

• Follicular Phase: 3.5 – 12.5 mIU/mL
• Ovulatory Phase: 4.7 – 21.5 mIU/mL
• Luteal Phase: 1.7 – 7.7 mIU/mL
• Postmenopausal: 25.8 – 134.8 mIU/mL

Males

• 1.5 – 12.4 mIU/mL

Interpretation of Results

• High FSH Levels:
  • Ovarian failure / menopause
  • Testicular failure
  • Gonadal dysgenesis
• Low FSH Levels:
  • Pituitary or hypothalamic disorders
  • Hormonal suppression

Methodology

• Chemiluminescent Immunoassay (CLIA) / Immunoassay

Reporting Time

• Typically Same Day / 24 Hours

Why Choose This Test?

• Accurate assessment of reproductive hormones
• Essential for infertility workup
• Helps guide hormonal therapy decisions
• Reliable and standardized testing method

Recommended With

• LH (Luteinizing Hormone)
• Prolactin
• Estradiol (E2)
• Testosterone