Fructosamine Test (F0010)

Test Name

Fructosamine

Test Code

F0010

Overview

The Fructosamine test measures glycated serum proteins, primarily albumin, to evaluate average blood glucose levels over the past 2–3 weeks. It serves as a short-term monitoring tool for glycemic control, especially when HbA1c testing is not reliable.

Clinical Significance

• Assesses short-term glucose control

• Useful in:

  • Diabetes management adjustments

  • Monitoring rapid changes in blood sugar levels

  • Situations where HbA1c may be inaccurate (e.g., anemia, hemoglobin variants)

Indications

• Diabetes mellitus monitoring

• Gestational diabetes follow-up

• Patients with hemoglobinopathies

• Recent changes in diabetes treatment

• Chronic kidney or liver disorders affecting HbA1c reliability

Sample Type

Serum

Preparation

• Fasting not required

• Inform physician about ongoing medications

Methodology

Colorimetric Assay

Reference Range

• 200 – 285 µmol/L (may vary by laboratory)

Interpretation

• Elevated Levels:

  • Poor glycemic control

  • Uncontrolled diabetes

• Decreased Levels:

  • Low protein states (e.g., nephrotic syndrome, liver disease)

Advantages

• Reflects recent glucose changes (2–3 weeks)

• Useful for quick treatment monitoring

• Not affected by red blood cell lifespan

Limitations

• Affected by serum protein levels

• Less standardized compared to HbA1c

Turnaround Time

Same day / 24 hours

Reporting Units

µmol/L

Suggested Use

Recommended alongside blood glucose or HbA1c for comprehensive diabetes management.

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