DNA QC

DNA QC – Test Content

Test Name: DNA QC (DNA Quality Control)

What is DNA QC?
DNA Quality Control is a laboratory assessment performed to evaluate the quality, quantity, purity, and integrity of extracted DNA before it is used for molecular genetic testing.

Why is DNA QC performed?

• Ensures extracted DNA is suitable for downstream testing
• Checks DNA concentration and purity
• Helps identify degradation or contamination
• Supports reliable PCR, sequencing, MLPA, and other molecular techniques
• Improves accuracy and consistency of genetic test results

Sample: DNA extracted from the submitted clinical specimen, as applicable.

Who may require DNA QC?
DNA QC is generally performed as part of the workflow for patients undergoing molecular genetic or genomic testing, especially when DNA quality can affect test performance.

Clinical Significance:
High-quality DNA is essential for dependable molecular analysis. Poor-quality or insufficient DNA may result in test failure, reduced coverage, or the need for repeat sample collection.

Report:
Results are interpreted according to the laboratory's validated DNA quality and quantity acceptance criteria.