DENGUE PROFILE (IgG, IgM, NS1), Quantitative, Serum
Overview
The Dengue Profile (IgG, IgM, NS1) is a comprehensive diagnostic panel designed to detect and monitor dengue infection at different stages. This test combines NS1 antigen detection (early infection) with IgM and IgG antibody analysis (immune response), providing a complete clinical picture for accurate diagnosis and disease progression assessment.
Why This Test is Important
Dengue fever can rapidly progress to severe complications if not diagnosed early. This profile helps:
- Detect early-stage infection (NS1 antigen)
- Identify recent infection (IgM antibodies)
- Determine past exposure or secondary infection (IgG antibodies)
- Support timely clinical decisions and treatment planning
Test Components
1. NS1 Antigen (Quantitative)
- Detectable from Day 1 of fever
- Indicates active viral infection
- Crucial for early diagnosis before antibodies develop
2. IgM Antibodies (Quantitative)
- Appears from Day 4–5 of infection
- Suggests recent or current infection
3. IgG Antibodies (Quantitative)
- Appears later and persists long-term
- Indicates past infection or secondary dengue infection
Who Should Take This Test
- Individuals with high fever, headache, joint/muscle pain
- Patients with suspected dengue symptoms
- Those living in or traveling to dengue-prone areas
- Patients requiring infection stage monitoring
Symptoms of Dengue
- High fever (sudden onset)
- Severe headache
- Pain behind the eyes
- Joint and muscle pain
- Skin rash
- Nausea or vomiting
- Mild bleeding (nose/gums)
Sample Required
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Specimen: Serum
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Method: ELISA / CLIA (Quantitative)
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Preparation: No fasting required
Turnaround Time
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Reports within: 24–48 hours
Clinical Significance
- Enables early detection and confirmation
- Differentiates between primary and secondary infections
- Helps prevent complications like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS)
Advantages of This Profile
- ✔ Complete dengue screening in one test
- ✔ Early + late stage detection
- ✔ Quantitative results for better monitoring
- ✔ Faster clinical decision-making
Precautions
- Test interpretation should be done by a qualified physician
- Correlate with clinical symptoms and other laboratory findings
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