Dengue IgM Antibody (Quantitative) By ELISA, Serum

Dengue IgM Antibody (Quantitative) by ELISA, Serum

Test Name: Dengue IgM Antibody (Quantitative) by ELISA
Sample Type: Serum
Method: Enzyme-Linked Immunosorbent Assay (ELISA)

About the Test

Dengue IgM Antibody testing detects and quantitatively measures IgM antibodies against Dengue virus in serum. IgM antibodies generally develop during the early phase of dengue infection and may remain detectable for several weeks.

Clinical Indications

• Suspected dengue infection with fever
• Fever with headache, body ache, rash or retro-orbital pain
• Evaluation of suspected recent dengue infection
• Supporting diagnosis when direct viral detection tests may no longer be optimal
• Monitoring suspected dengue infection in the appropriate clinical context

Sample Requirements

• Sample: Serum
• Specimen: Blood
• Follow laboratory instructions for collection and handling.

Methodology

ELISA – a laboratory immunoassay used for detection and quantitative assessment of Dengue-specific IgM antibodies.

Interpretation

• Positive: Dengue IgM antibodies are detected at a significant level, supporting a recent or current dengue infection. Clinical correlation is required.
• Negative: Dengue IgM antibodies are not detected or are below the assay's detection threshold. Early testing may produce a negative result before antibodies become detectable.
• Equivocal/Borderline: Repeat testing and clinical correlation may be recommended according to laboratory protocol.

Important Note

A single IgM result should not be interpreted in isolation. The timing of fever onset, clinical findings and other dengue investigations should be considered by the treating physician.