Dengue IgG Antibody (Quantitative) by ELISA, Serum – D0002a
Test Overview
The Dengue IgG Antibody (Quantitative) test by ELISA is a serological assay used to measure the concentration of IgG antibodies against the dengue virus in serum. This test helps determine past exposure, immunity status, or secondary dengue infection.
Principle of the Test
This test is based on the Enzyme-Linked Immunosorbent Assay (ELISA) technique, where dengue-specific antigens bind to IgG antibodies present in the patient’s serum. The intensity of the reaction is measured and reported quantitatively, reflecting antibody levels.
What Does the Test Detect?
- Detects IgG antibodies against dengue virus (DEN-1, DEN-2, DEN-3, DEN-4)
- Indicates past infection or long-term immune response
- Helps identify secondary dengue infections
- IgG antibodies typically appear 7–10 days after infection and may persist for years or lifelong
Clinical Significance
- Confirms previous dengue infection
- Assesses immune status in endemic regions
- Supports diagnosis of secondary dengue (more severe cases)
- Useful for serosurveillance and epidemiological studies
When is the Test Recommended?
- History of dengue-like illness
- Suspected past dengue infection
- Differentiation between primary and secondary infection
- Follow-up after dengue infection
Sample Type
Preparation
- No fasting required
- Inform your physician about any medications
Test Method
- Quantitative ELISA (Enzyme-Linked Immunosorbent Assay)
Result Interpretation (Indicative – may vary by lab)
| Result |
Interpretation |
| Negative |
No detectable IgG antibodies (no past exposure or very low levels) |
| Equivocal |
Borderline – repeat testing advised |
| Positive |
Past dengue infection or secondary infection |
- High IgG levels may indicate recent past infection or secondary dengue
- Rising titres in paired samples may suggest recent infection
Limitations
- Cannot confirm current active infection alone
- May show cross-reactivity with other flaviviruses
- Should be interpreted along with IgM/NS1 tests and clinical findings
Turnaround Time
- Typically same day / within 24 hours (varies by lab)
Why Choose This Test?
- Accurate quantitative measurement
- Helps assess dengue immunity
- Useful in clinical diagnosis & research
Keywords (SEO)
Dengue IgG ELISA Test, Dengue Antibody Test, Quantitative Dengue Test, Dengue Serum Test, Dengue Immunity Test, IgG Dengue Detection
