Cytomegalovirus (CMV) Detection (Qualitative) by Real-Time PCR
Test Name: Cytomegalovirus (CMV) Detection – Qualitative by Real-Time PCR
Purpose:
Detects the presence of Cytomegalovirus (CMV) DNA in the submitted clinical specimen using a highly sensitive molecular technique.
Clinical Indications:
- Suspected active CMV infection
- Evaluation of CMV infection in immunocompromised patients
- Monitoring suspected congenital or neonatal CMV infection
- Investigation of CMV-related symptoms in transplant recipients
- Assessment of CMV infection in patients with unexplained systemic or organ-specific manifestations
Method:
Real-Time Polymerase Chain Reaction (RT-PCR)
Sample Type:
Depends on clinical indication and laboratory protocol; commonly EDTA whole blood/plasma, urine, CSF, or other appropriate clinical specimens.
Result:
Reported qualitatively as:
-
Detected – CMV DNA detected
-
Not Detected – CMV DNA not detected
Interpretation:
A Detected result indicates the presence of CMV DNA in the tested specimen and should be interpreted along with clinical findings and other laboratory investigations. A Not Detected result does not completely exclude CMV infection, particularly when viral load is low or the specimen is collected at an inappropriate stage of infection.
Key Advantage:
Real-time PCR provides rapid and highly sensitive molecular detection of CMV DNA, making it useful for identifying active infection when clinically indicated.
Note: Test performance, specimen requirements, and interpretation may vary depending on the specimen type and laboratory methodology.
