Clostridium Difficle Toxin A and B, GDH, Rapid, Stool

Clostridium difficile Toxin A & B, GDH, Rapid, Stool

Sample Type: Stool

Test Overview:
The Clostridium difficile (C. difficile) Toxin A & B, GDH Rapid Test is used to detect Glutamate Dehydrogenase (GDH) antigen and Toxins A & B produced by Clostridium difficile in stool samples. This rapid test helps diagnose C. difficile infection (CDI), a common cause of antibiotic-associated diarrhea and healthcare-associated intestinal infections.

Why is this test done?

• Diagnose Clostridium difficile infection (CDI)
• Evaluate persistent or severe diarrhea after antibiotic use
• Detect toxin-producing C. difficile strains
• Support early treatment decisions
• Help prevent infection spread in healthcare settings

Symptoms that may require this test:

• Frequent watery diarrhea
• Abdominal pain or cramping
• Fever
• Nausea
• Loss of appetite
• Dehydration
• Blood or mucus in stool (in some cases)

Preparation:

• No fasting is required.
• Collect a fresh stool sample in a sterile container.
• Avoid contamination with urine or water.
• Inform your doctor about recent antibiotic use or ongoing medications.

Method:
Rapid Immunochromatographic Assay (GDH Antigen & Toxin A/B Detection)

Reporting Time:
Same day / Within 24 hours (may vary by laboratory)

Interpretation:

• GDH Positive, Toxin Positive: Indicates active C. difficile infection.
• GDH Positive, Toxin Negative: Suggests C. difficile organism may be present; additional molecular testing may be recommended.
• GDH Negative, Toxin Negative: C. difficile infection is unlikely.

Who should get tested?

• Patients with persistent diarrhea after antibiotic therapy
• Hospitalized patients with unexplained diarrhea
• Individuals suspected of healthcare-associated infections
• Immunocompromised patients
• Elderly individuals with gastrointestinal symptoms

Note:
This test should be interpreted along with clinical symptoms and medical history. Additional confirmatory testing may be recommended when results are inconclusive.