CK5/6 by IHC

CK5/6 by IHC

Test Name: CK5/6 (Cytokeratin 5/6) by Immunohistochemistry (IHC)

Sample Type: Tissue Biopsy / Paraffin-Embedded Tissue Block

Test Overview:
CK5/6 is an immunohistochemical marker used in pathology to identify the expression of Cytokeratin 5 and Cytokeratin 6 proteins in epithelial cells. It is valuable in the diagnosis and classification of various tumors, particularly squamous cell carcinomas and mesotheliomas, and helps differentiate them from other malignancies.

Clinical Significance:

• Assists in the diagnosis of squamous cell carcinoma.
• Helps distinguish mesothelioma from adenocarcinoma.
• Useful in the classification of lung, breast, bladder, and head & neck tumors.
• Supports tumor origin identification when used alongside other IHC markers.
• Aids pathologists in accurate cancer diagnosis and treatment planning.

Methodology:
Immunohistochemistry (IHC)

Reporting:

• Positive or Negative staining pattern
• Intensity and distribution of staining
• Interpretation by a qualified pathologist

Applications:

• Oncology diagnostics
• Tumor classification
• Differential diagnosis of epithelial malignancies
• Histopathological evaluation