Chromosomal Microarray(CMA 750 K) - Affymetrix Cytoscan 750K_ONCO

Chromosomal Microarray (CMA 750K) – Affymetrix CytoScan 750K_ONCO

Test Overview

Chromosomal Microarray Analysis (CMA 750K) using the Affymetrix CytoScan 750K platform is a high-resolution genomic test designed to detect chromosomal abnormalities across the entire genome. It identifies clinically significant copy number variations (CNVs) such as microdeletions, microduplications, regions of homozygosity (ROH), and loss of heterozygosity (LOH) that may be associated with genetic disorders and certain cancers. The CytoScan 750K array contains over 750,000 genomic markers, enabling precise genome-wide analysis.

What Does This Test Detect?

• Chromosomal microdeletions and microduplications
• Copy Number Variations (CNVs)
• Loss of Heterozygosity (LOH)
• Regions of Homozygosity (ROH)
• Uniparental Disomy (UPD) indications
• Genomic imbalances associated with congenital disorders and oncology conditions

Recommended For

• Developmental delay or intellectual disability
• Autism spectrum disorders
• Multiple congenital anomalies
• Unexplained genetic disorders
• Prenatal cases with abnormal ultrasound findings
• Oncology patients requiring genomic copy number analysis

Sample Required

• Peripheral Blood / Bone Marrow / Prenatal Sample (as advised by the clinician)

Benefits

✅ Genome-wide high-resolution analysis
✅ Detects abnormalities not visible on routine karyotyping
✅ Identifies clinically relevant CNVs with greater sensitivity
✅ Supports diagnosis, prognosis, and genetic counseling
✅ Valuable tool for both constitutional and oncology genetic investigations

Why Choose Advanced BioCare Laboratories?

• Advanced genomic testing platform
• Expert interpretation by molecular genetics specialists
• Accurate and reliable reporting
• Comprehensive support for clinicians and patients

Advanced BioCare Laboratories – Delivering Precision Genomic Diagnostics for Better Healthcare Decisions.