CD14 Count by Flow Cytometry, Whole Blood

Test Overview

The CD14 Count by Flow Cytometry test measures the number and percentage of CD14-positive monocytes in peripheral blood. CD14 is a surface marker primarily expressed on monocytes and macrophages and plays an important role in the body's innate immune response. Flow cytometry enables accurate identification and quantification of these cells, supporting the evaluation of immune system status and various hematological and inflammatory disorders.

Why is this Test Done?

• Assessment of monocyte populations in blood
• Evaluation of immune function and immune activation
• Monitoring inflammatory and infectious conditions
• Supportive investigation in hematological disorders
• Research and clinical studies involving monocyte subsets
• Monitoring response to immunomodulatory therapies

Symptoms / Conditions Associated

A CD14 count may be useful in patients with:

• Recurrent infections
• Chronic inflammatory conditions
• Autoimmune disorders
• Suspected immune dysfunction
• Hematological malignancies
• Sepsis and systemic inflammatory conditions

Specimen Required

• Sample Type: Whole Blood
• Collection Tube: EDTA (Lavender Top) Tube
• Method: Flow Cytometry

Preparation

• No special preparation is usually required.
• Inform your healthcare provider about any ongoing medications or recent treatments.

Interpretation

• Normal CD14 levels: Indicate a normal monocyte population.
• Elevated CD14 Count: May be associated with inflammatory conditions, infections, immune activation, or certain hematological disorders.
• Reduced CD14 Count: May indicate impaired monocyte production, immune suppression, or bone marrow-related conditions.

Results should always be interpreted in conjunction with clinical findings, patient history, and other laboratory investigations.

Benefits of the Test

• Accurate quantification of monocytes
• Helps assess immune system health
• Supports diagnosis and monitoring of inflammatory disorders
• Useful in hematology and immunology evaluations
• Provides rapid and reliable results through flow cytometry

Test Details

Reliable immune cell profiling for comprehensive assessment of monocyte populations and immune function.

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