CD117 (Myeloid Marker), Bone Marrow

CD117 (Myeloid Marker), Bone Marrow

What is the CD117 (Myeloid Marker), Bone Marrow Test?

CD117 (also known as c-KIT) is a cell surface marker detected by Flow Cytometry on a bone marrow sample. It helps identify immature blood-forming cells (blasts) and supports the diagnosis and classification of various blood cancers and bone marrow disorders.

Why is this test done?

Your doctor may recommend this test to:

• Diagnose Acute Myeloid Leukemia (AML)
• Evaluate bone marrow disorders
• Differentiate types of leukemia
• Assess abnormal myeloid cell populations
• Support treatment planning and disease monitoring

When is it recommended?

This test may be advised if you have:

• Persistent unexplained anemia
• Frequent infections
• Easy bruising or bleeding
• Abnormal CBC results
• Suspected leukemia or other hematological malignancies

Sample Required

• Sample Type: Bone Marrow Aspirate

Test Method

• Flow Cytometry (Immunophenotyping)

Preparation

• No special preparation is usually required.
• Follow your hematologist's instructions before the bone marrow procedure.

Benefits

• Helps accurately classify leukemia
• Supports early diagnosis of bone marrow diseases
• Assists in selecting appropriate treatment
• Provides valuable information alongside other myeloid markers

Note: CD117 is interpreted as part of a comprehensive immunophenotyping panel. Results should always be evaluated together with clinical findings, blood counts, bone marrow morphology, cytogenetic, and molecular studies.

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