Cardiolipin IgG & IgM Antibody, Serum
Test Overview
The Cardiolipin IgG & IgM Antibody test measures the presence of anticardiolipin antibodies in the blood. These autoantibodies are associated with autoimmune disorders, particularly Antiphospholipid Syndrome (APS), which can increase the risk of blood clots, recurrent miscarriages, and other vascular complications.
Why This Test is Done
- Diagnose or evaluate Antiphospholipid Syndrome (APS)
- Investigate unexplained blood clots (thrombosis)
- Assess recurrent pregnancy loss or pregnancy-related complications
- Support the diagnosis of autoimmune disorders such as lupus
- Monitor patients with known antiphospholipid antibodies
Symptoms and Conditions Associated
- Deep vein thrombosis (DVT)
- Stroke or transient ischemic attacks (TIA)
- Recurrent miscarriages
- Pregnancy complications
- Unexplained clotting disorders
- Systemic lupus erythematosus (SLE)
Sample Required
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Sample Type: Serum
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Preparation: No special fasting required unless advised by your physician.
Interpretation of Results
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Negative: No significant anticardiolipin antibodies detected.
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Positive IgG and/or IgM: May indicate Antiphospholipid Syndrome or other autoimmune conditions.
- Results should be interpreted along with clinical findings and additional laboratory tests.
Clinical Significance
Persistent elevation of anticardiolipin antibodies is a key laboratory criterion for diagnosing Antiphospholipid Syndrome. Early detection helps identify individuals at risk for thrombotic events and pregnancy-related complications, enabling timely medical management.
Precautions
- Antibody levels may fluctuate over time; repeat testing may be recommended.
- Clinical correlation is essential for accurate diagnosis.
- Inform your healthcare provider about any autoimmune conditions or medications.
