Breast Cancer Gene Panel – Comprehensive (ONCO)
Test Overview
The Breast Cancer Gene Panel – Comprehensive (ONCO) is an advanced genetic test designed to identify inherited and clinically significant mutations associated with breast cancer susceptibility. Using Next-Generation Sequencing (NGS) technology, this panel analyzes multiple cancer-related genes to help assess hereditary cancer risk, guide treatment decisions, and support personalized cancer management.
Why is this Test Recommended?
This test is useful for individuals who:
- Have a personal history of breast cancer
- Have a family history of breast, ovarian, pancreatic, or prostate cancer
- Developed breast cancer at a young age
- Have multiple affected family members across generations
- Require genetic information for targeted therapy selection
- Need hereditary cancer risk assessment for family planning
Genes Commonly Included
The comprehensive panel may include clinically relevant genes such as:
- BRCA1
- BRCA2
- PALB2
- TP53
- ATM
- CHEK2
- PTEN
- CDH1
- STK11
- NBN
- RAD51C
- RAD51D
- BARD1
- BRIP1
- Additional cancer predisposition genes as per panel design
Clinical Applications
- Hereditary breast cancer risk assessment
- Identification of inherited cancer syndromes
- Personalized treatment planning
- Targeted therapy eligibility evaluation
- Family member risk assessment and screening guidance
- Genetic counseling support
Sample Required
Technology Used
- Next-Generation Sequencing (NGS)
- Bioinformatics Variant Analysis
- Variant Classification according to international guidelines
Benefits of Testing
✔ Early identification of genetic cancer risk
✔ Supports precision oncology approaches
✔ Helps optimize screening and surveillance strategies
✔ Assists in treatment selection and prognosis assessment
✔ Enables preventive measures for at-risk family members
Preparation
No special preparation or fasting is required.
Reporting
The report provides:
- Detected pathogenic or likely pathogenic variants
- Variants of uncertain significance (if applicable)
- Clinical interpretation
- Recommendations for genetic counseling and follow-up
Important Note
A positive result indicates the presence of a genetic variant associated with increased cancer risk but does not guarantee cancer development. Results should always be interpreted in conjunction with clinical findings, family history, and genetic counseling.
Advanced BioCare Laboratories offers comprehensive oncology genetic testing with high-quality sequencing and expert interpretation to support precision cancer care.
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