Borreliosis-IgG by Western Blot

Borreliosis – IgG by Western Blot

Borreliosis – IgG by Western Blot is a confirmatory blood test used to detect IgG antibodies against Borrelia bacteria, the organism responsible for Lyme disease (Borreliosis). This test helps support the diagnosis of current or past infection, especially in patients with persistent symptoms or positive screening results.

Why This Test Is Done

• Confirmation of suspected Lyme disease
• Evaluation after a positive/equivocal ELISA test
• Investigation of chronic joint, neurological, or skin symptoms
• Monitoring immune response to Borrelia infection

Symptoms That May Require Testing

• Bull’s-eye skin rash
• Fever and fatigue
• Muscle and joint pain
• Headache and neck stiffness
• Facial paralysis
• Tingling or numbness
• Neurological symptoms

Test Method

Western Blot Technique

Sample Required

Blood / Serum Sample

Preparation

• No fasting required
• Inform your doctor about ongoing medications or recent infections

Interpretation

• Positive IgG: Indicates past exposure or later-stage infection with Borrelia
• Negative IgG: No detectable long-term antibodies
• Results should always be correlated with clinical symptoms and medical history

Recommended For

• Individuals with suspected Lyme disease
• Patients with persistent unexplained neurological or joint symptoms
• People with history of tick exposure or travel to endemic regions

Reporting Time

Usually 3–7 working days

Note

This test is a confirmatory assay and is often performed after an initial Lyme disease screening test. Clinical correlation is essential for accurate diagnosis.