BIOPSY (AFB Stain)

BIOPSY (AFB Stain)

BIOPSY (AFB Stain) is a specialized laboratory test used to detect Acid-Fast Bacilli (AFB) in biopsy tissue samples. It helps diagnose infections caused by Mycobacterium tuberculosis and other mycobacterial organisms.

Why This Test is Done

• Detects tuberculosis (TB) in tissue samples
• Identifies mycobacterial infections in organs or lymph nodes
• Helps evaluate chronic inflammation or granulomatous lesions
• Assists in confirming infectious causes in biopsy specimens

Sample Required

• Biopsy tissue sample

Method

• Special AFB staining technique (Ziehl–Neelsen / Auramine stain)

Benefits

• Early detection of tissue TB infection
• Supports accurate diagnosis and treatment planning
• Useful in cases where routine staining is inconclusive

Preparation

• Usually no special preparation required
• Follow physician instructions regarding biopsy procedure

Reporting Time

• Typically 2–4 days depending on laboratory processing