The Bilirubin (Total and Direct), Serum test measures the levels of bilirubin in the blood. Bilirubin is a yellow pigment produced when red blood cells break down. The liver processes bilirubin and helps remove it from the body through bile.
This test helps evaluate liver function and diagnose conditions affecting the liver, gallbladder, and blood cells.
Sample Type
Serum
Why is this Test Done?
Assess liver health and function
Diagnose jaundice (yellowing of skin and eyes)
Detect liver diseases such as hepatitis and cirrhosis
Evaluate bile duct obstruction
Monitor treatment and progression of liver disorders
Investigate causes of abnormal liver function tests
Parameters Measured
Total Bilirubin: Measures both direct and indirect bilirubin in the blood.
Direct (Conjugated) Bilirubin: Bilirubin processed by the liver and ready for excretion.
When is this Test Recommended?
Yellowing of skin or eyes (jaundice)
Dark-colored urine
Pale stools
Abdominal pain or swelling
Unexplained fatigue
Suspected liver or gallbladder disease
Preparation
Fasting may be recommended based on your doctor's advice.
Inform your healthcare provider about any medications you are taking.
Normal Reference Range
Total Bilirubin: 0.3 – 1.2 mg/dL
Direct Bilirubin: 0.0 – 0.3 mg/dL
(Reference ranges may vary slightly between laboratories.)
Interpretation
Elevated Total Bilirubin: May indicate liver disease, hemolytic anemia, or bile duct obstruction.
Elevated Direct Bilirubin: Often suggests liver dysfunction or blockage in bile flow.
Normal Levels: Generally indicate healthy bilirubin metabolism and liver function.
Benefits of the Test
Early detection of liver disorders
Helps diagnose causes of jaundice
Supports monitoring of liver disease treatment
Assists in evaluating bile duct and gallbladder conditions
Reliable liver health assessment with accurate bilirubin measurement for timely diagnosis and management.