The Bicarbonate, Serum test measures the level of bicarbonate (HCO₃⁻) in the blood. Bicarbonate is an important electrolyte that helps maintain the body’s acid-base (pH) balance. This test is commonly used to evaluate metabolic and respiratory conditions, kidney function, and electrolyte balance.
Why is the Bicarbonate, Serum Test Done?
Doctors may recommend this test to:
Assess acid-base balance in the body
Diagnose metabolic acidosis or alkalosis
Monitor kidney and lung disorders
Evaluate dehydration or electrolyte imbalance
Monitor treatment in critically ill patients
Investigate symptoms such as confusion, weakness, vomiting, or breathing problems
Symptoms That May Require Testing
Shortness of breath
Fatigue or weakness
Confusion
Persistent vomiting or diarrhea
Rapid breathing
Muscle twitching or cramps
Normal Reference Range
Typical bicarbonate levels in adults are:
22 – 29 mEq/L
Reference ranges may vary slightly depending on the laboratory and testing method.
What Do Abnormal Results Mean?
Low Bicarbonate Levels
May indicate:
Metabolic acidosis
Kidney disease
Diabetic ketoacidosis
Severe diarrhea
Lactic acidosis
Shock or severe infection
High Bicarbonate Levels
May indicate:
Metabolic alkalosis
Chronic lung disease
Excessive vomiting
Dehydration
Use of certain diuretics
Sample Required
Sample Type: Serum
Preparation: Usually no fasting required unless advised by the doctor