Beta hCG by IHC (Immunohistochemistry)
Test Name: Beta hCG by IHC
Sample Type: Tissue (Paraffin-embedded tissue block/slides)
Purpose of the Test:
Beta Human Chorionic Gonadotropin (β-hCG) by Immunohistochemistry (IHC) is used to detect the presence of β-hCG protein expression in tissue samples. This test assists pathologists in identifying trophoblastic tumors, germ cell tumors, and certain other malignancies that may produce β-hCG.
Why is this Test Done?
- Helps diagnose trophoblastic diseases.
- Assists in the evaluation of germ cell tumors.
- Supports tumor classification and differentiation.
- Aids in determining the origin of metastatic tumors.
- Provides additional information for treatment planning and prognosis.
Conditions Associated with Positive β-hCG Expression:
- Choriocarcinoma
- Gestational trophoblastic neoplasia
- Germ cell tumors
- Embryonal carcinoma
- Some ovarian tumors
- Certain lung, gastrointestinal, and other malignancies
Benefits of the Test:
- Highly specific tissue-based marker detection.
- Supports accurate tumor diagnosis.
- Helps differentiate between various tumor types.
- Assists clinicians in making informed treatment decisions.
Preparation Required:
No special patient preparation is required. Tissue specimens should be collected and preserved according to standard pathology protocols.
Turnaround Time:
Typically 3–7 working days, depending on laboratory workflow and specimen requirements.
Reporting:
Results are reported by a qualified pathologist along with interpretation of staining pattern, intensity, and clinical significance.
