Beta-2-Crosslaps (Ctx-1), EDTA Plasma

EDTA Whold Blood/ heparin plasma

Beta-2-Crosslaps (CTX-1), EDTA Plasma

Overview

Beta-2-Crosslaps (CTX-1) is a biochemical marker used to evaluate bone resorption — the process where bone tissue is broken down and minerals are released into the bloodstream. CTX-1 testing helps assess bone metabolism and is commonly used in the diagnosis and monitoring of conditions such as osteoporosis and other metabolic bone disorders.

Why This Test is Done

• Assess bone turnover rate
• Diagnose osteoporosis and osteopenia
• Monitor effectiveness of osteoporosis treatment
• Evaluate fracture risk
• Detect metabolic bone diseases
• Monitor bone health in postmenopausal women

Sample Type

• EDTA Plasma

Preparation

• Overnight fasting may be recommended
• Morning sample collection is preferred due to daily variation in CTX levels
• Inform your doctor about ongoing medications or supplements

Normal Reference Range

Reference values may vary depending on age, gender, and laboratory methodology.

Increased Levels May Indicate

• Osteoporosis
• Increased bone resorption
• Hyperparathyroidism
• Bone metastasis
• Paget’s disease

Decreased Levels May Indicate

• Effective anti-resorptive therapy
• Reduced bone turnover

Clinical Significance

CTX-1 is considered a sensitive marker for monitoring bone loss and treatment response. Serial measurements can help clinicians evaluate whether bone-protective therapy is working effectively.

Turnaround Time

Usually 1–3 days, depending on laboratory workflow.