BCL-6 with H-Score by IHC

Overview

BCL-6 with H-Score by Immunohistochemistry (IHC) is a specialized diagnostic test used to evaluate the expression of the BCL-6 protein in tissue samples. BCL-6 is a transcription factor commonly associated with certain lymphomas and other malignancies. The H-Score method provides a semi-quantitative assessment of staining intensity and distribution, helping clinicians understand the level of protein expression more accurately.

Why This Test is Done

• To assist in the diagnosis of lymphoma subtypes
• To evaluate BCL-6 protein expression in tumor tissues
• To support prognosis and treatment planning
• To differentiate between germinal center and non-germinal center lymphomas
• To aid oncologists in targeted therapy decisions

Sample Required

• Formalin-Fixed Paraffin-Embedded (FFPE) tissue block or slides

Methodology

• Immunohistochemistry (IHC) with H-Score analysis

Test Highlights

• Accurate semi-quantitative scoring of BCL-6 expression
• Helps in precise tumor characterization
• Valuable for hematopathology and oncology evaluation
• Performed by experienced histopathology professionals
• Reliable support for clinical decision-making

Who Should Consider This Test?

This test may be recommended for patients with suspected or diagnosed lymphomas and other cancers where BCL-6 expression analysis is clinically significant.

Reporting Time

• Typically within 5–7 working days

Note

Test interpretation should always be correlated with clinical findings, histopathology, and other laboratory investigations.

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