Allergen – Aspergillus IgE Antibody, Serum

Test Overview

The Allergen – Aspergillus IgE Antibody, Serum test measures specific IgE antibodies against Aspergillus species in the blood. Aspergillus is a common environmental fungus that can trigger allergic reactions, especially in individuals with asthma, allergic rhinitis, or respiratory sensitivity.

This test helps identify fungal allergy sensitization and supports the diagnosis of allergic respiratory conditions.

Common Aspergillus Species Tested

• Aspergillus fumigatus
• Aspergillus niger
• Aspergillus flavus (depending on panel)

Purpose of the Test

This test is used to:

• Detect allergy to Aspergillus fungus
• Evaluate unexplained respiratory allergies
• Support diagnosis of:
  • Allergic asthma
  • Allergic rhinitis
  • Allergic bronchopulmonary aspergillosis (ABPA)
• Monitor patients with chronic fungal allergy symptoms

Symptoms Associated with Aspergillus Allergy

• Sneezing
• Nasal congestion
• Wheezing
• Chronic cough
• Breathlessness
• Chest tightness
• Eye irritation
• Recurrent asthma attacks

Sample Required

• Sample Type: Serum
• Method: Immunoassay / EIA / FEIA
• Preparation: No fasting required

Reference Range

Reference values may vary by laboratory.

Clinical Significance

Elevated Aspergillus-specific IgE levels may indicate:

• Fungal hypersensitivity
• Environmental mold allergy
• Asthma associated with fungal sensitization
• Allergic bronchopulmonary aspergillosis (ABPA)

This test should be interpreted along with clinical history and other allergy investigations.

Who Should Get Tested?

• Individuals with chronic respiratory allergies
• Asthma patients with worsening symptoms
• People exposed to damp or moldy environments
• Patients with recurrent wheezing or fungal sensitivity suspicion

Notes

• A positive result indicates sensitization, not necessarily active disease.
• Additional allergy panels or total IgE testing may be recommended.
• Clinical correlation is essential for diagnosis.